Ukudla kwe-ketogenic kungasiza kanjani ekwelapheni ubuchopho obuvuzayo futhi kwenze umgoqo wegazi nobuchopho uqine futhi uqine ngokwengeziwe?
Isikhathi sokufunda esilinganiselwe: 17 imizuzu
Lowo ngumbuzo omuhle ngempela. Ngakho ngizoyiphendula. Kulo mbhalo webhulogi, sizodingida ukuthi iyini isithiyo sobuchopho begazi, yiziphi izimpawu esingalindela ukuthi zenzeke uma konakala futhi kuvuza, ngisho nokuhlolwa kwelebhu okungasetshenziswa ukuzama ukuhlola ukuthi kuvuza yini.
Isithiyo sakho sobuchopho begazi (BBB) sibaluleke kakhulu.
Okokuqala, i-anatomy encane kanye nomsebenzi. Kwanele nje ukuze uqonde ukuthi yini ehilelekile.
I-BBB ihlukanisa igazi ku-extracellular cerebrospinal fluid futhi ivikela ubuchopho emagciwaneni atholakala egazini kanye nobuthi kuyilapho ivumela ukusakazeka komoyampilo, i-carbon dioxide, nama-lipophilic molecules/ethanol. Ukugcinwa kwe-BBB kubalulekile ukuze kulawulwe ngokuqinile ukwakheka kwamakhemikhali oketshezi lwe-brain's interstitial (ISF) olubalulekile ekusebenzeni kwe-synaptic kanye nokunikeza uhlobo lokuvikela emagciwaneni atholakala egazini.
Kakaroubas, N., Brennan, S., Keon, M., & Saksena, NK (2019). I-Pathomechanism yokuphazamiseka kwesithiyo sobuchopho begazi ku-ALS. Ijenali ye-Neuroscience, 2019. https://doi.org/10.1155/2019/2537698
I-BBB iqoqo lemithambo yegazi nama-astrocyte agcina izinto ziphuma ebuchosheni ekujikelezeni kwesistimu. Inezithuthi ezihlukene ezivumela ukuthi ezinye izinto zidlule.
Kodwa njengethumbu elivuzayo njengoba i-BBB iyancipha empilweni ayikwazi ukugcina ubuqotho bayo futhi izinto zingena ebuchosheni okungafanele. Lokhu kungase kuhlanganise:
- Amakhemikhali kanye Nobuthi Bemvelo
- Amagciwane (amabhaktheriya nama-virus)
- Amaprotheni okudla (isb, gluten)
- Abalamuli abahlukahlukene bokuvuvukala egazini (isb, lipopolysaccharide)
- Ama-anti-body ajikelezayo
- Ukungalingani kweHormone (hypothyroidism yeqiniso)
Lapho lezi zinto zidlula emgodleni ovuzayo wegazi nobuchopho zenza amasosha omzimba obuchopho asebenze ukuze azame ukuvikela ubuchopho. Ngokukhethekile, amaseli e-microglial ayasebenza. Uma une-BBB evuzayo, kusho ukuthi izinto ziphakama ngaso sonke isikhathi okungezona ezakho. Futhi lokhu kusho ukuthi ukusebenza kwe-microglial kwenzeka njalo. Akulungile lokho. Lokho kusetha isiteji se-neuroinflammation engapheli. Futhi uma ubuchopho bakho bungakwazi ukuzilungisa ngokushesha ngokwanele ukuhambisana nomonakalo oqhubekayo obangelwa yi-neuroinfigueation engapheli, kuzokumisela inqubo ye-neurodegenerative.
Ubuchopho budinga ama-micronutrients ukulungisa umonakalo, ukwenza ama-neurotransmitters nama-enzyme abalulekile, kanye nokukhiqiza amandla. Uyazi ukuthi ubuchopho bakho buwathola kanjani amavithamini amaningi adingekayo kulezo zinqubo? I-BBB yakho. Yebo, kunjalo! Iningi lamavithamini abalulekile ancibilikayo emanzini (isb., amavithamini B) namanye ama-metabolite abalulekile athuthelwa ebuchosheni kusetshenziswa izithuthi ezithile ku-BBB.
Ezinye zalezi zithuthi zisetshenziselwa ukudlulisa i-glucose ebuchosheni. Njengoba sixoxile ezihlokweni ezedlule, lokhu akudingekile ukuthi kube yi-glucose oyidlayo. Umzimba wakho ujabule kakhulu ukwenza i-glucose substrate oyidingayo ukuze izingxenye ezithile zobuchopho bakho zisebenze. Kodwa uma i-BBB yakho ilimele futhi izithuthi ezisetshenziselwa leyo njongo zilimele noma zingasebenzi (i-BBB ingaba ukumelana ne-insulin) lapho-ke ngeke ukwazi ukusebenzisa leyo glucose ukuze uthole amandla. Futhi ngale ndlela, ukuwohloka kwe-BBB kungenzeka futhi ukuwohloka kwayo kuqhubekisele phambili izinkinga zamandla ebuchosheni.
Uma i-BBB yakho ilimele, lokho kungabangela inkinga kubo bonke labo bathuthi, umsebenzi wabo uwukuthola imisoco kanye nophethiloli ebuchosheni bakho.
Lokhu kusho ukuthi ubuchopho bakho buguga ngokushesha KAKHULU kunalokho obekufanele kwenze. Futhi akunandaba ukuthi uneminyaka engu-15 noma 27 noma 34 noma uneminyaka engu-40 noma engu-50 noma engu-60. Izinqubo ze-Neurodeergenerative zenzeka kunoma yisiphi isikhathi. I-BBB evuzayo akuyona inkinga yomuntu omdala. “Iyinkinga yawo wonke umuntu wanoma iyiphi ubudala.” Futhi idinga ukucatshangelwa futhi kubhekwane nayo.
Ungangizwa kabi. Ngiyajabula ukubona iGUT evuzayo ithola i-airtime nokukhathazeka okuningi. Ngikhululekile ekugcineni kuma-radar abantu ngendlela yangempela. Ukuphulukisa amathumbu avuzayo kubalulekile ngoba udinga ukugcina amasosha omzimba ethule ukuze amasosha omzimba obuchopho angasebenzi ngokweqile. Udinga amapheshana okugaya anempilo ukuze ukwazi ukudiliza futhi umunce imisoco yakho emathunjini akho futhi udinga i-microbiome enempilo cishe ngezizathu eziyinkulungwane.
Ungafunda kabanzi mayelana nama-microbiomes anempilo lapha.
Kodwa kunesinye isithiyo esidinga ukukhuthazwa futhi siqondwe ngumphakathi jikelele kanye nabantu abalwa nobuchopho obungasebenzi ngendlela abebengathanda ngayo. Futhi yingakho lokhu okuthunyelwe kubhalwa. Ubuchopho obuvuzayo buyinto.
Uma i-BBB iphukile into enkulu eyenzekayo ukuthi uthola i-neuroinflammation. Uma kunenqubo ye-neuroinflammatory, abantu baqala ukukhononda ngokuba nezimpawu zenkungu yobuchopho.
Uma unenkungu yobuchopho, kusho ukuthi kukhona okuphazamisa ukusebenza okuvamile kwe-synapse.
Ama-Synapses akha ingxenye ekhethekile kakhulu nebalulekile yamaseli e-neuronal. Ziyizindawo eziyinhloko zokuxhumana phakathi kwamaseli e-neuronal, ngakho-ke, abandakanyeka kuzo zonke izici ze-neuronal physiology. Ukusebenza kahle kwe-synaptic kuyisidingo somsebenzi ojwayelekile wobuchopho, futhi nokuphazamiseka okuncane kungaholela ekuphazamisekeni kwezinzwa.
Xylaki, M., Atzler, B., & Outeiro, TF (2019). I-Epigenetics ye-Synapse ku-Neurodegeneration. Imibiko yamanje ye-neurology ne-neuroscience, 19(10), i-1-10. https://doi.org/10.1007/s11910-019-0995-y
I-Neuroinflammation iphazamisa isivinini sokuqhuba izinzwa futhi ungase uqaphele ukuthi ukucabanga kanye nemisebenzi yemoto iyancipha ukusebenza kahle noma iza kalula. I-Neuroinflammation iphinde "ihlukanise" i-mitochondria. I-Mitochondria yimithombo yakho yamandla yamaseli. Banikeza amandla ingqamuzana lakho eliwadingayo ukuze lisebenze. Ukusuka ekudubuleni lawo ma-synapse kuya ekugcineni iseli liphilile linamandla okwenza ukugcinwa kwamaseli okuyisisekelo. Izizwa kanjani i-mitochondria engahlanganisiwe? Kuzwakala njengokukhathala kwengqondo. Ingqondo yakho ikhathala ngokushesha. Mhlawumbe awusakwazi ukushayela esiminyaminya, ukumelana nokuxhumana okude noma ukufunda okuningi ngendlela obujwayele ukwenza ngayo. Amandla akho okwenza imisebenzi nokunaka ayancipha.
I-Neuroinflammation ingakhula futhi iphele. Kwamanye amasonto kuba nokuphazamiseka kwemizwa kanye nokuphazamiseka kwengqondo, kanti kwamanye amasonto uzobhekana nalezo zimpawu ezincane. Lokhu kumane kusho ukuthi ubuchopho buba nempumelelo ethile, kwesinye isikhathi, ukuphatha inqubo yokuvuvukala nokulungisa ukuwohloka kwemizwa njengoba kwenzeka.
Kodwa njengoba ungase ucabange, izimbangela ezidala i-BBB evuzayo akufanele zishaywe indiva, futhi ngesinye isikhathi inkungu yobuchopho ingase ingapheli, njengoba isimiso somzimba sokuzivikela ezifweni sisebenza ngokweqile futhi izinga okwenziwa ngalo umonakalo lidlula izimiso zokulwa ne-antioxidant emzimbeni. , ukudala ingcindezi ye-oxidative kanye nokuqalisa izinqubo ezibalulekile ze-neurodegenerative.
Ubufakazi obukhulayo bubonisa ukuthi i-oxidative stress (OS) idlala indima ebalulekile ekwenziweni kwezinguquko ze-BBB.
Kadry, H., Noorani, B., Bickel, U., Abbruscato, TJ, & Cucullo, L. (2021). Ukuhlolwa okuqhathaniswayo kwe-in vitro BBB tight junction ubuqotho kulandela ukuchayeka entuthuni kagwayi nomhwamuko we-e-cigarette: Ukuhlolwa komthamo wemiphumela yokuvikela ye-metformin kusetshenziswa omaka be-paracellular-cell-molecular-weight encane. Uketshezi kanye Nezithiyo ze-CNS, 18(1), i-1-15. https://doi.org/10.1186/s12987-021-00261-4
Ngilokhu ngibalula lezi “zinqubo” ze-neurodeergenerative ngoba ngenkathi ukuwohloka kwemithambo-luvo kwenzeka ngezikhathi ezithile, uma sekudlulele ekubeni into engapheli (okuyinqubo) i-neurodegeneration iyaziphakela yona, idale iluphu lomonakalo oqhubekayo, ukuncipha komsoco, i-neuroinflammation eyengeziwe, nezinye izici ezingayenza. kunzima kakhulu ukuyiguqula ngemva kwephuzu elithile lomonakalo. Uma kuvunyelwa ukuthi kungahloliwe kungabangela izinga lomonakalo ongeke ukwazi ukulungiseka. Futhi yingakho le bhulogi ikhala i-alamu yokuthi inkungu yobuchopho idinga ukuthathwa ngokungathi sína futhi ilashwe ngokwelashwa okunamandla okunomsoco kanye nokusebenza kwengqondo okumisa izimbangela zezinqubo ze-neurodegenerative. Kungakhathaliseki isizathu noma ukuxilongwa.
Ngazi kanjani uma nginobuchopho obuvuzayo?
Kukhona ama-antibody marker ahlukene ahlotshaniswa ne-BBB permeability. Lokhu kufaka phakathi i-S100B, i-aquaporin 4, iphrotheni ye-glial fibrillary acidic, namasosha omzimba e-zonulin. Udokotela wakho osebenzayo anga-oda ukuhlolwa okufana nalokhu ngeCyrus Laboratory.
Ungahlolwa, kodwa nansi into. Uma wazi ukuthi unethumbu elivuzayo, noma kutholakale ukuthi unethumbu elivuzayo, maningi amathuba okuthi ube ne-BBB evuzayo. Ngoba ithumbu elivuzayo livumela izinto ukuthi zingene egazini okungafanele. Futhi ezinye zalezo zinto ukuhlasela okuqondile ku-BBB. Ukuhlobana phakathi kwamathumbu avuzayo kanye ne-BBB evuzayo kuphezulu kakhulu. Bahamba ndawonye.
Isibonelo, amasosha omzimba akhiqizwa ngokumelene ne-gluten, angavinjwa yi-BBB angabopha kuma-astrocyte namaphrotheni e-neurofilament ku-cerebellum futhi abangele isimo esibizwa ngokuthi i-Gluten Ataxia. Inqubo ye-neurodeergenerative eholela kulokhu kuxilongwa ingase ibukeke njengezimpawu zenkungu yobuchopho ezihlanganisa ukukhuluma nenkinga, ukuzwa okuzwakalayo okungavamile emaphethelweni, ukungasebenzi kahle nokulinganisela, futhi mhlawumbe izinkinga ngokusebenzisa izingalo nemilenze yakho noma iminwe nezandla (isb. qaphela izinkinga eziningi zokwenza iminwe yakho isebenze ngenkathi ukhilosha).
Mhlawumbe unobuthi emzimbeni wakho, noma ngabe ngokuchayeka ekhemikhalini eliphuma emkhiqizweni wasendlini ojwayelekile noma into oyihogele endaweni ohlala kuyo uhamba emgwaqweni (lokhu kwenzeka njalo). Uma i-BBB yakho inempilo, lezi ngeke zidlulele ebuchosheni. Kodwa uma kungenampilo, noma iyiphi into ezowela ngayo ebuchosheni, isebenze i-microglia ekhulula ama-cytokines avuvukalayo.
Lezi zinto ezingamukelekile ezikwenze kwaba nge-BBB yakho, futhi akufanele zibe noma yikuphi eduze nobuchopho, zizobopha futhi zinamathisele kumaprotheni ahlukene futhi ziphule izinto. Ngiqonde ukuthini ngokuthi “phula izinto” ngokuqondile? Ngiqonde ukuthi bazobophezela ezindaweni ezinye izinto obekufanele ziboshwe kuzo, futhi zingavumeli okuthile ukuthi kusebenze kahle. Bazongena endleleni futhi bavimbele izindlela ezibalulekile ezidingwa ubuchopho bakho ukuze busebenze futhi ugcine ubuchopho bakho buphilile.
I-BBB yakho yavuza kanjani
I-BBB yakho ngokuyisisekelo ingamaseli endothelial nama-astrocyte (i-astroglia). Kokubili lokhu konakaliswa kalula ezindaweni zokuvuvukala okungapheli. Izifo ezingamahlalakhona ezandisa ukuvuvukala emzimbeni (okungenzeka ukuthi zonke) zingabamba iqhaza ekubhidlizeni i-BBB. Eminye yemithi esetshenziswa umuthi ojwayelekile ukwelapha isifo esingamahlalakhona ingabangela ukuwohloka kwe-BBB (isb., i-corticosteroids). Kungase futhi kwenzeke ngenxa yokulimala kobuchopho okubuhlungu (TBI) (isb., izingozi zemoto, ukuwa) ngoba i-BBB ingase ingapholi ngokwanele ngemva kokuhlaselwa okunjalo. Izinkinga zamathumbu ezivuvukalayo ezingapheli zingadala isimo sokuvuvukala kwesistimu ngenxa yokuvuza kwamathumbu (ukungena kwamanzi) okukhulula i-zonulin noma i-lipopolysaccharides (LPS) eyengeziwe egazini, bese kuthikameza impilo ye-BBB ngokuqondile.
Yini enye edala izinkinga ku-BBB yami?
Uma unamazinga aphezulu e-homocysteine ekuhlolweni kwegazi lakho, unethuba eliphezulu lokuthi i-BBB yakho iyavuza. Uma une-SNP yofuzo efana ne-MTHFR, usengozini enkulu yezinkinga zokugcina i-BBB yakho injalo futhi inempilo. Ungathuthukisa izingqinamba ngokuthatha i-methylated B-complex.
Ezinye izici ezidala ukungena kwe-BBB zifaka okulandelayo:
- Indlela yokuphila yama-sedentary
- Ukuphuza utshwala
- Ukungalali okungapheli
Cishe ungathanda ukwazi ukuthi yini engenziwa ukuyilungisa.
Ukudla kwe-ketogenic kungasiza kanjani ukwelapha ubuchopho obuvuzayo
Ulwazi lwethu oluningi mayelana nokuthi ama-ketones ayithinta kanjani i-BBB luvela ezifundweni zezilwane. Ngokwami lokho kuyangikhulula. Angifuni kube khona osika umuntu ekhanda ezama ukuthola ukuthi kwenzakalani lapho. Ngakho-ke ungaxhonywa emcabangweni wokuthi ngenxa yokuthi lezi zivela ezifundweni zezilwane ngandlela thize okutholakele akukona okusemthethweni ku-BBB yakho. Kunemishini eminingi efanayo eqhubekayo.
Ubuchopho obuthuthukisiwe kanye ne-BBB metabolism
Uma umzimba wakho wenza ama-ketone ekudleni kwe-ketogenic, unganikeza omunye umthombo wamandla we-BBB eyonakele. Zimane nje zingumthombo wamafutha okhethwayo wobuchopho. Zingena ebuchosheni ngaphandle kwengxabano noma ukuxokozela kokudinga isithuthi esijabulayo noma esisebenzayo (isb., ukusabalalisa okulula noma ukusabalalisa okulula). Izithuthi ze-Monocarboxylate zilamula ukungena komzimba we-ketone ebuchosheni, futhi ziyinsada kuyo yonke i-BBB, okuhlanganisa nolwelwesi lwe-plasma lwe-choroid plexus, amangqamuzana e-endothelial kanye ne-epithelial, i-glia, nama-neurons. Eqinisweni, ama-oodle wezindlela zokwenza lawo ma-ketone akhuphuke lapho ukuze aphembelele ubuchopho bakho. Lawo ma-ketone asetshenziswa ku-matrix ye-mitochondrial (ulwelwesi lwamabhethri eseli lakho) elenza amandla.
Nakhu engikudingayo nawe ukuthi ukuthole. I-BBB isebenzisa amandla avela kuma-ketone futhi. Lawo maseli amancane akha i-BBB azama ukuzenzela amandla asekelwe kwi-ketone ngaso sonke isikhathi. Futhi uma udla ukudla okune-ketogenic lawo maseli azogcwala amandla awadingayo ukuze aqinise ukuhlangana okudingekayo ukuze kugcinwe i-BBB iqinile futhi ingaguquki.
Ngike ngasho ukuthi ubuchopho budinga amandla amaningi? Kuhle impela ukuthi kunendlela yokuyithola amandla ewadingayo engadingi umzamo owengeziwe. Kulungile? Kufana nokungena kancane esikhundleni sokuthenga isiko lokuphithizela. Ngisho ukuthi, singathola lawo ma-receptors e-GLUT asebenze futhi ekugcineni njengoba ukuphulukiswa kwethu kuqhubeka. Kodwa ngeke sithuthuke ekwelapheni kwethu uma silambisa ubuchopho okwamanje. Kumane kuqhubekisele phambili izinqubo ze-neurodegenerative eziqhubekayo. Njengebhonasi, imizimba ye-ketone iphinde ithuthukise umsebenzi we-GLUT1 ngokuqondile, futhi i-GLUT1 iyisithuthi esiza ukuthi i-glucose ifike lapho ifanele.
Ama-ketones ane-anti-inflammatory
Asinayo nje imithi enikeza izinga elifanayo lemiphumela eqeda ukuvuvukala ngokuphepha noma ngempumelelo njengokudla kwe-ketogenic.
Ukuphumelela kokwelapha kwezidakamizwa ze-anti-neuroinflammatory ezibanzi kunqunyelwe imiphumela yazo engemihle ngemva kokucindezelwa ngisho nokuzivikela kwesikhashana.
JANIGRO, D. (2022). Imiphumela ye-Ketogenic Diet ku-Blood-Brain Barrier. Ukudla kwe-Ketogenic kanye Nokwelashwa Kwe-Metabolic: Izindima Ezandisiwe Kwezempilo Nezifo, 346. P.355
Uma kunokusebenza kokuzivikela komzimba okungamahlalakhona kuba nomonakalo owenziwa ebuchosheni kanye naku-BBB. Lokhu kubangela ukuvuvukala nokucindezeleka okwengeziwe komzimba ekuzameni ukugcina ukuhlangana okuqinile ku-BBB. Lokhu kuvuvukala kungalimaza lezo zakhiwo ezibalulekile ze-vascular eziyingxenye ye-BBB. Ingalimaza i-glial nama-astrocyte. Izidlo ze-Ketogenic zinciphisa ukuvuvukala. Ama-ketones akhiqizwa ekudleni kwe-ketogenic aziphatha njengama-molecule abonisayo, etshela ngokoqobo izakhi zofuzo ezihilelekile ekuvuvukeni okungapheli ukuthi zizicime. Iwusizo kakhulu ekusizeni leyo BBB encane ukuthi ithole ukulungiswa, igcine ubuqotho nokusebenza kwayo, futhi iqhubekisele phambili ukuphulukiswa kwayo uma ungibuza.
Manje buyela kulezo zakhiwo ze-vascular. Kunezinhlobo eziningi zokuwohloka komqondo ezinezingxenye zesifo semithambo. Ama-ketones akhulisa ukugeleza kwegazi lobuchopho futhi lokhu kukhuphuka kwegazi nokusetshenziswa komoyampilo kucatshangwa ukuthi nomthelela emiphumeleni ye-neuroprotective ebhalwe kahle yemizimba ye-ketone. I-BBB evuzayo iyisici se-etiological kokunye ukuwohloka komqondo (isb, i-Alzheimer's) futhi kucatshangwa ukuthi izinzuzo ezibonwa ngokudla okune-ketogenic kulezi zibalo ngokwengxenye zingabangelwa ukusebenza kwe-BBB okuthuthukisiwe. I-hypothesis yokuthi ama-ketone athuthukisa ukusebenza kwe-neurovascular ekuwohlokeni komqondo iyindawo yamanje yocwaningo locwaningo.
Njengokungathi konke lokhu bekungacabangi ngokwanele ukusebenzisa ukudla kwe-ketogenic ukusiza ukwelapha ubuchopho obuvuzayo, ama-ketones asiza ukudala amaprotheni amaningi i-BBB ewasebenzisayo ukuphulukisa lezo zindawo zegebe ezivuzayo, ekuqaleni.
Izinketho Zokwengeza
Ngenxa yokuthi ngikholwa ukuthi unelungelo lokwazi zonke izindlela ongazizwa ungcono ngazo, ngizobhala ezinye zezithasiselo ezisetshenziswayo ezinamazinga ahlukahlukene obufakazi bokuthuthukisa i-BBB. Kodwa mangicacise kahle ngokuthi angicabangi ukuthi lokhu kuseduze njengokupholile noma kusebenza ngempumelelo ekwelapheni i-BBB njengokudla okune-ketogenic okwakhiwe kahle. Akukho kulokhu okwelapha ukumelana ne-insulin. Akukho kulokhu okungenye yemithombo kaphethiloli yobuchopho. Ezinye zalezi zingathuthukisa umsebenzi nokugeleza kwegazi kumangqamuzana e-epithelial kanye ne-endothelial, kanti ezinye zinganikeza isenzo esithuthukisiwe se-antioxidant ukuze uzame ukudlala ukubamba ukucindezeleka okwenziwe nge-oxidative.
Ingabe uzothola ukuphulukiswa kwe-BBB kulezi zithako? Yebo, ungase. Inqobo nje uma i-neurodegenerative cascade oqhubekayo ayinawo umfutho omningi. Kodwa uma ukungena kwakho kwe-BBB kubangelwa unhlangothi noma i-TBI, noma izinqubo zokuwohloka komqondo kwangaphambi kwesikhathi, lezi azihlinzeki ngomthombo wamafutha ofanele ubuchopho bakho budinga ukulwa ne-hypometabolism yobuchopho. Lezi zithako azihlinzeki ngama-micronutrients athuthukisiwe noma ngisho nama-macronutrients ukuze kugcinwe futhi kulungiswe ubuchopho obuthuthukisiwe nomsebenzi we-BBB.
Uma uzimisele ngokuphilisa ubuchopho bakho, ungesabi ukwenza into oyicabangayo inzima ngempela. Ngiyakwethembisa, ukuthi ukufunda indlela yokusebenzisa kanye nokugcina ukudla okune-ketogenic akunzima kangako njengokuba nobuchopho obungasebenzi. Ingqondo ekuvimbela ukuthi ujabulele impilo ngokugcwele.
Ubuchopho obulokhu bucindezelekile ngezinkinga zemizwa nezinkinga zenkumbulo?
KUNZIMA LOKHO. Njalo. Awushadile. Usuku.
Ukudla kwe-ketogenic kuyijika lokufunda futhi ufanele ukwesekwa ekuyisebenziseni. Kodwa ngiyakwethembisa, njengomuntu oselule ingqondo yami, akunzima njengoba ucabanga. Usuvele udlula kwenye yezinto ezinzima kakhulu. Ukudla kwe-Ketogenic kulula uma kuqhathaniswa.
Izithasiselo ezingasiza ekulungiseni i-BBB zifaka amafutha ezinhlanzi, i-Ginko Bilboa, i-vinpocetine, i-alpha-lipoic acid, i-glutathione (thola i-liposomal noma izandulela ezibalulekile, funda ukuthi kungani lapha), kanye ne-resveratrol.
Ngezinye izikhathi ngizosebenzisa okunye kwalokhu ngaphezu kokudla kwe-ketogenic njengokwelashwa okungeziwe, kodwa angizisebenzisi ngokwazo ukuze ngiphulukise ama-BBB noma ezinye izingxenye zobuchopho. Ngakho-ke, angiyazi imithamo eqondile esetshenziswa abantu uma besebenzisa lokhu njengokwelapha okuyinhloko ngale njongo. Kodwa futhi, uzokwazi ukucwaninga lezo ziguquguqukayo ukuze uphulukise ngokwakho.
Isiphetho
Ohlelweni Lokubuyiselwa Kwenkungu Yobuchopho engifundisayo, sisebenzisa ukudla okune-ketogenic, ukwesekwa okunomsoco okulungiselelwe wena siqu, kanye nokuqeqesha mayelana nokungenelela kwemithi esebenzayo okusiza ukwelapha i-BBB evuzayo nokusiza abantu baphile impilo yabo engcono kakhulu. Ngoba masithembeke. Uyithola kanjani impilo? Ngobuchopho bakho. Akudingeki uphile nezimpawu zenkungu yobuchopho, kungakhathaliseki isizathu noma ukuxilongwa. Ngenxa yokuthi udokotela wakho akazinakanga izikhalazo zakho mayelana nokungakwazi kwakho ukugxila, ukukhumbula izinto, noma ukugcina isimo sakho sengqondo akusho ukuthi azikho izindlela zokwelapha ezisebenzayo.
Ngiyajabula ukukusiza ufunde zonke izindlela ongazizwa ungcono ngazo!
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