I-Glutathione kanye nokudla kwe-ketogenic

I-ketogenic diet's upregulation of glutathione idlala kanjani indima ekwelapheni ubuchopho bakho ekuguleni kwengqondo kanye nokuphazamiseka kwemizwa?

I-Glutathione iwuhlelo oluyinhloko lwe-antioxidant ebuchosheni. Ikhono lokudla kwe-ketogenic lokulawula ukukhiqizwa kwe-glutathione liwusizo ikakhulukazi kubantu abanesifo sengqondo noma ukuphazamiseka kwemizwa. Izidlo ze-Ketogenic zandisa ukukhiqizwa kwe-glutathione ebuchosheni. Ezinye izindlela lapho i-glutathione iphatha khona ukugula kwengqondo kanye nezinkinga zezinzwa ukulungisa amathumbu avuzayo, ukunciphisa ukuvuvukala kobuchopho ngokuphendula okuthuthukisiwe kwamasosha omzimba wama-macrophage, ukulungiswa okuthuthukisiwe kwesithiyo sobuchopho-gazi (BBB). Ukuthuthukiswa kokukhiqizwa kwe-glutathione nakho kuthuthukisa ukusebenza kwesibindi, okunciphisa umthwalo wokuhlaselwa emzimbeni okungase kuthikameza ukusebenza kobuchopho kamuva (isb., izinsimbi ezisindayo, i-xenoestrogens).

Isingeniso

Uma ufunde kakhulu nhlobo kule bhulogi, ufunde mayelana nokuvuvukala nokucindezeleka okwenziwe nge-oxidative, nokuthi lezo zingakha kanjani izimpawu zokugula kwengqondo nokuphazamiseka kwezinzwa. Kungenzeka futhi ukuthi ufunde lokho engikubhalile mayelana nohlelo olumangalisayo lwe-anti-oxidant onalo emzimbeni wakho olusiza ukulwa nokuvuvukala nokucindezeleka okwenziwe nge-oxidative. Lokhu okungapheli (umzimba wakho uyawenza!) I-antioxidant i-glutathione futhi ukukhiqizwa kwakho kwe-glutathione kwanda uma uhamba ekudleni kwe-ketogenic.

Lokhu okuthunyelwe kuzoxoxa ngokuthi kungani ukulawulwa kwe-glutathione okuthola ekudleni kwe-ketogenic kubaluleke kakhulu ekwelapheni ukugula kwakho kwengqondo noma izinkinga zezinzwa. Sizokhuluma ngokuqondile ngokuthi kungani amandla okudla kwe-ketogenic okulawula i-glutathione kungenye yezindlela ezinkulu esiza ukwelapha izimpawu zakho.

Okunye okuthunyelwe kwebhulogi (kuyeza maduze!) kuzoxoxa ngokuthi iyini i-glutathione, yenziwa kanjani emzimbeni wakho, nokuthi yini ongayenza ukuze ukhulise ukukhiqizwa kwakho kwe-glutathione okungapheli okuzokwenza ngcono imiphumela yokuphulukisa kakade yokudla kwakho kwe-ketogenic yokugula kwengqondo.

Kodwa okokuqala, ake sikhulume ngokuthi kungani udinga i-glutathione elawulwayo oyithola ekudleni kwe-ketogenic, ikakhulukazi ukwelapha ukugula kwakho kwengqondo nokunciphisa izimpawu zakho.

I-Glutathione yelapha i-Leaky Gut yakho.

Kungenzeka ukuthi uqale ukudla kwakho kwe-ketogenic ngezinkinga zokugaya ezinobunzima obuhlukahlukene. Lapho befunda abantu abane-irritable bowel syndrome, bathola izimpawu zokuthi i-glutathione iyancipha. Lokhu kungenxa yokuthi ihlale incishwa emizamweni yayo yokulwa nengcindezi ye-oxidative emathunjini.

Ake sithi ayikho i-glutathione eyanele yokunciphisa ukuvuvukala nokulwa nokucindezeleka okwenziwe nge-oxidative. Uma kunjalo, uthola ukulimala kwamangqamuzana, okukunikeza lezo zimpawu ezimbi zokugaya ukudla. Njengoba amazinga e-glutathione encipha, amathumbu awakwazi ukuzilungisa, avuze. Amathumbu avuzayo ngaphezulu enza amasosha omzimba wakho asebenze, akhuphule umsebenzi wokuzivikela ebuchosheni kanye ne-neuroinflammation.

I-Neuroinflammation iyisici esiyisisekelo ku-pathology yazo zonke izifo zengqondo engibhale ngazo kule bhulogi kuze kube manje. Sonke siyazi ukuthi impilo yamathumbu ethu ithinta impilo yobuchopho bethu nomoya wethu. 

Ngakho-ke ngenkathi usekudleni kwakho kwe-ketogenic futhi i-glutathione yakho ilawulwa, uzogcina ukucindezeleka okwenziwe nge-oxidative phansi emathunjini akho. Lokho kuzosiza amathumbu akho alulame (ekugcineni) futhi, futhi, wehlise i-neuroinflammation yakho namazinga wokucindezeleka okwenziwe nge-oxidative ebuchosheni bakho. Futhi leyo kungenye yezindlela ukudla kwe-ketogenic okuzokusiza ukwelapha ukugula kwakho kwengqondo. 

I-Glutathione kanye namasosha omzimba wakho

Abantu abadla ukudla okune-ketogenic baphawula ukuthi abaguli kakhulu futhi abagula kakhulu. Ungase uzibuze ukuthi kumayelana nani lokho. Kunezindlela eziningi ezibalulekile ukuthi ukudla kwe-ketogenic kuthuthukisa ukusebenza kwamasosha omzimba. Kodwa ngokuqondile ukuthi ukudla kwe-ketogenic kwandisa kanjani i-glutathione nokuthi ukukhiqizwa okuthuthukisiwe kwe-glutathione kuthuthukisa kanjani amasosha omzimba, sidinga ukukhuluma ngama-macrophages. I-glutathione eyanele iyadingeka ukwenza amangqamuzana amhlophe egazi (ama-macrophage) abe ingxenye ebalulekile yamasosha omzimba.

Ama-macrophage anempilo ngenani elanele akhiqiza ukuzivikela okusheshayo nokubalulekile ekuhlaseleni amagciwane namagciwane. Ufuna ukusabela okuqinile, okusheshayo, nokuchoboza kwamasosha omzimba kubahlaseli. Ongakufuni yimpi ende, edonswe ngaphandle, futhi engasebenzi egcina ama-cytokines avuvukalayo ephezulu futhi eqhubeka nokudala ukuvuvukala kobuchopho isikhathi eside. 

I-Glutathione kanye nesithiyo sakho sobuchopho begazi

Umgoqo wakho wegazi nobuchopho kungenzeka ukuthi uyavuza uma unesifo sengqondo noma ukuphazamiseka kwemizwa. Futhi lokhu kuyinkinga enkulu. Udinga lowo mgoqo wegazi nowobuchopho uqinile futhi usebenze kahle ukuze uvikele ubuchopho bakho kubuthi. Uma kungenjalo, ama-molecule obekungamelwe asondele ebuchosheni bakho enza lokho kanye. Lokhu kubangela ukusabela komzimba ebuchosheni bakho ukulwa nalawo ma-molecule okungafanele abe khona. Le mpendulo yokuzivikela komzimba ebuchosheni bakho ikhiqiza ama-cytokines avuthayo. Lawa ma-cytokines akhiqiza ukulimala kwamaselula njengoba ezama ukulwa nosongo. Okungaba kuhle ukube besingenalo inqwaba yamangqamuzana angena ebuchosheni okungafanele abe khona ngenxa yesithiyo esivuzayo sobuchopho begazi. I-neuroinflammation engapheli eba khona ngenxa yokungami kwamasosha omzimba obuchopho ngenxa yokuvuza kwesithiyo sakho segazi nobuchopho kuyimbangela eyinhloko yezimpawu zakho.  

Kwenzeka kanjalo nje ukuthi ukudla kwe-ketogenic kuthuthukisa ukulungiswa nokugcinwa kwesithiyo sobuchopho begazi ngezindlela ezihlukahlukene. Okokuqala, bathuthukisa ukwakhiwa kwezikhala ezinhle, eziqinile, okuyingxenye ye-BBB evuzayo. Izidlo ze-Ketogenic nazo zandisa ukukhiqizwa kwamandla kuma-astrocyte, okungenye yemizimba eyinhloko ye-neuronal ephethe impilo ye-BBB.  

Ngakho-ke, imiphumela enenzuzo yokudla kwe-ketogenic ingase incike ekuthathweni kobuchopho okwandisiwe [kwemizimba ye-ketone] ama-KB ukuze ihambisane nesidingo se-metabolic kanye nokulungiswa kwe-BBB ephazamisekile.

Ama-CellKB alawula phezulu ukufuduka kweseli kanye nokuvezwa kwamaprotheni e-gap junction Banjara, M., & Janigro, D. (2016). Imiphumela yokudla kwe-ketogenic kusithiyo segazi nobuchopho. KUkudla kwe-etogenic kanye Nemithi Yokwelapha Ye-Metabolic: Izindima Ezandisiwe Kwezempilo Nezifo; Susan, AM, Ed, 289-304. I-DOI: 10.1093/med/9780190497996.001.0001

Ukulawulwa kwe-glutathione ekudleni kwe-ketogenic kusiza ukugcina nokulungisa umgoqo wegazi nobuchopho. 

I-Glutathione nesibindi sakho

Isibindi sakho asikwazi ukukhipha ubuthi emzimbeni wakho ekuhlaselweni kwemvelo ngaphandle kwamazinga anele e-glutathione. Ukuhlaselwa kwemvelo okungahloliwe, kungakhathaliseki ukuthi kudlula umgoqo wakho wegazi nobuchopho, kungadala i-neuroinflammation. 

Isibindi sidinga i-glutathione ukuze ikusize ukukhiphe ubuthi obuvela kulawa ma-inhibitors alandelayo ukuya empilweni yakho yengqondo. Ngayinye yalezi ifanelwe ukuthunyelwe okuhlukile ukuchaza ukuthi zifaka isandla kanjani ekuthuthukisweni kokuphazamiseka kwengqondo. 

• ama-metabolites ezidakamizwa
• i-mycotoxins
• izinsimbi ezisindayo
• izibulala-zinambuzane
• ukhula
• ama-xenoestrogens   

Udinga ukulawulwa kwe-glutathione okwenzeka ekudleni kwe-ketogenic ukuze usize umzimba wakho we-detox ezintweni ezilimaza impilo yakho yobuchopho futhi udale izimpawu zakho. 

I-Glutathione nengqondo yakho

Ake ngicacise kahle. I-Glutathione I-ANTIOXIDANT EYINHLOKO esetshenziswa ubuchopho bakho ukuze uzigcine unempilo futhi usebenza. Akuyona i-Vitamin C futhi ayiyona i-Vitamin E, nakuba lezo zisetshenziswa njengama-cofactors ukwenza i-glutathione. Uma ufuna ubuchopho obunempilo, ufuna i-glutathione eningi njengoba umzimba wakho ufuna ukukhiqiza ukuvikela nokulungisa ama-neurons emonakalweni.

Ake sithi unesifo sengqondo noma ukuphazamiseka kwemizwa. Uma kunjalo, cishe unezingxenye zobuchopho bakho eziphansi kakhulu ku-glutathione. Ezinye zezindawo zobuchopho ezitholakala ziphansi kakhulu ku-glutathione ezinkingeni ezithile zifaka okulandelayo:

• I-Lower posterior cingulate cortex ku-Obsessive-Compulsive Disorder (OCD)
• I-Substantia nigra ku-Parkinson's Disease (PD)
• I-Occipital ne-prefrontal cortex ekucindezelekeni
• I-Prefrontal cortex ku-Bipolar Disorder kanye ne-Schizophrenia

Ukwandisa ukukhiqizwa kwe-glutathione kungasiza ukulwa nengcindezi ye-oxidative ezingxenyeni ezithile zobuchopho ezihambisana nokuxilongwa kwakho okuthile. Ngaleyo ndlela kunciphisa izimpawu zakho.  

Ngisho noma amazinga e-glutathione ehlile engakatholakali ezakhiweni ezithile zobuchopho zesifo sakho, kukhona ukuvumelana okuphelele ezincwadini zokuthi ukuxilongwa kwengqondo nemizwa kuye kwanda amazinga okucindezeleka okwenziwe nge-oxidative kanye namazinga aphansi e-glutathione ngokujwayelekile. 

I-Glutathione (GSH) ngokungangabazeki iyi-antioxidant ebaluleke kakhulu ebuchosheni. Eminyakeni yamuva nje, amazinga e-GSH ahlanekezelwe afakwe ezinkingeni ezehlukene zengqondo, okuhlanganisa ne-psychopathologies ehlobene nokucindezeleka.

Zalachoras, I., Hollis, F., Ramos-Fernández, E., Trovo, L., Sonnay, S., Geiser, E., Preitner, N., Steiner, P., Sandi, C., & Morató, L. (2020). Amandla okwelapha e-glutathione-enhancers kuma-psychopathologies ahlobene nokucindezeleka. Ukubuyekezwa kwe-Neuroscience kanye nokuhlolisisa impilo, 114, 134-155. https://doi.org/10.1016/j.neubiorev.2020.03.015

Ngakho-ke, ukusebenzisa ukudla kwe-ketogenic ukukhulisa amazinga e-glutathione ebuchosheni kungenye yezindlela okuyindlela yokwelapha esebenzayo yesifo sakho sengqondo noma ukuphazamiseka kwengqondo. 

Isiphetho

Ziningi izinzuzo zomuntu onenkinga yokugula ngengqondo noma izimpawu zemizwa ukukhulisa ukukhiqizwa kwe-glutathione. Futhi i-ketogenic yenza lokho kanye!

Manje, ungase ube nomehluko othile wofuzo ophazamisa ikhono lakho lokwenza nokuvuselela i-glutathione. Kungase kube nzima kuwe ukukwenza, futhi lokho kungaba usizo ukwazi. Uma ufuna ukungena ujule emandleni omzimba wakho okwenza i-glutathione, ngingancoma ukuhlolwa ngokusebenzisa 23andMe (isixhumanisi). Khumbula, ingxenye yakho 23andMe ungakhokhelwa nge-akhawunti yakho yokonga impilo (HSA) noma (i-FSA) uma unaleyo nzuzo.

Lapho usunayo i- 23andMe idatha ongayibhalisela le webhusayithi emangalisayo I-Genetic Life Hacks (isixhumanisi esihlobene) esizosihlaziya futhi sibike ukuthi izakhi zofuzo zakho zisekela kahle kangakanani ikhono lakho lokwenza nokusebenzisa kabusha lesi sibulala-magciwane esibalulekile ubuchopho bakho obuphulukisayo budinga kabi kakhulu!

https://www.geneticlifehacks.com/gst-glutathione-detoxification/

Kungakhathaliseki ukuthi utholani, ungalilahli ithemba. Kunezinto esingayenza ukuze sikhulise ukukhiqizwa kwakho kwe-glutathione, ngisho nokudla kwe-ketogenic, okwenza umsebenzi omuhle kakhulu wokwenza okuningi kwasekuqaleni.

Udinga ukufunda lesi sihloko mayelana nokuntuleka kwe-thiamine ngoba ukushoda kwe-thiamine kungaphazamisa ikhono lakho lokwenza i-glutathione. Futhi kungenzeka ukuthi ungena ekudleni kwakho kwe-ketogenic thiamine okushodayo! 

Ukushoda kwe-thiamine kungalimaza kanjani ukudla kwakho kwe-ketogenic empilweni yengqondo

Qiniseka ukuthi uthola i-magnesium eningi, njengoba lokho kwenza i-thiamine isebenze, ngakho ingenza into yayo ukusiza ukwenza i-glutathione.

Uma uthole lesi sihloko esingenhla siwusizo, ungase futhi uthande lokhu okunye okuthunyelwe kwebhulogi kuxoxa nge-glutathione.

Ukudla kwe-Ketogenic kwelapha ukugula kwengqondo - Ingxenye 3

Ngingumeluleki wezempilo yengqondo owenza izimiso zokwelapha zengqondo ezisebenzayo nezomsoco. Ngithuthukise uhlelo lwe-inthanethi njengothisha kanye nomqeqeshi wezempilo osebenzayo ukuze ngisebenzele umphakathi kangcono, ngizama ukufunda ukuthi bangazizwa kanjani bengcono. Ungafunda kabanzi mayelana nohlelo lokubuyiswa kwe-Brain Fog ngezansi:

Uhlelo Lokubuyisela Inkungu Yengqondo

Uyakuthanda lokho okufunda kubhulogi? Ingabe ufuna ukufunda mayelana nama-webinars azayo, izifundo, ngisho neminikelo ezungezayo yosekelo nokusebenzisana nami ekufezeni imigomo yakho yokuphila kahle? Bhalisela!

Free Brain Nutrition Guide

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